Biostatistics
What is a p-value?
P-values show how large the probability is to obtain the observed test results assuming the null hypothesis is correct. Or in other words, how likely
P-values show how large the probability is to obtain the observed test results assuming the null hypothesis is correct. Or in other words, how likely
A test of significance consists of four steps. First, the null and alternative hypothesis must be stated. Second, the test must be chosen appropriately, and
When applying a statistical test, there are always two hypotheses as a basis. The null hypothesis describes the non-favorable scenario, where the investigational product would
In every clinical trial, statistics play a very important part. Because based on the statistical analysis, decisions are made about new therapies, medicaments, or medical
When conducting a clinical trial one of the most important aspects is to define the objective of a study and to decide on what the
When it is about the precision of a test result, confidence intervals are a more useful measure than p-values, which only reflect the statistical significance. Confidence intervals provide additional information about how large the effect could be, so answering the question how the clinical relevance for the finding is.
An example for a point estimator is the arithmetic mean when trying to find the mean of a population. A point estimator is used to
The uniform distribution is probably the simplest of all probability distributions. It is used for data, where all outcomes within a predefined interval have the
The Poisson distribution is modelling the number of events within a defined time interval or area. For example, counting variables such as the recruitment for
If an outcome variable that can be specified in two response possibilities only, data can be analyzed as binary based on a binomial distribution, where each observation of a defined number of “experiments” represents one of the two outcomes, and the probability of success is the same for each observation.
In this part of our blog series accompanying our #video #series “5 Minutes Statistics for Clinical Trials” we explain what a #binomial #distribution reflects and what are its characteristics.
